Medicube - One Day Exosome Shot Pore Ampoule 25000 (13ml)

medicube One Day Exosome Shot Pore Ampoule 25000 is an intensive once-weekly pore and texture treatment combining micro-spicule technology with Lactobacillus Extracellular Vesicles, Milk Exosomes, Niacinamide, Panthenol, exfoliating acids and three peptides. Hydrolyzed Sponge creates the product’s characteristic micro-needling-like tingling sensation while the formula targets enlarged-looking pores, excess sebum, rough texture, dullness and uneven-looking skin. Designed for experienced pore-care routines, it is applied as the first skincare step after cleansing and followed with soothing, hydrating products.

Benefits:

• Provides intensive pore care: Clinical testing reported improvements in visible pore density, area, volume and overall pore appearance.
• Helps refine uneven texture: Hydrolyzed Sponge spicules create a distinctive micro-textured application experience while Gluconolactone, Betaine Salicylate and Citric Acid support smoother-looking skin.
• Helps remove accumulated surface cells: PHA, BHA-related exfoliation and the spicule-based format help improve rough, congested-looking texture.
• Supports brighter-looking skin: Niacinamide helps improve dullness and uneven-looking tone while supporting the moisture barrier.
• Helps balance excess sebum: The formula supports a clearer, more refined-looking complexion in oily and combination skin.
• Supports the skin barrier: Panthenol, Ceramide NP, Hydrogenated Lecithin and humectants help maintain hydration and skin comfort.
• Provides exosome-focused skincare: Lactobacillus Extracellular Vesicles and Milk Exosomes are clearly included in the supplied formula.
• Contains three peptides: Acetyl Tetrapeptide-5, Palmitoyl Pentapeptide-4 and Palmitoyl Tripeptide-5 provide additional smoothing and elasticity-focused care.
• Helps improve radiance: Supplied testing reported a significant improvement in measured skin radiance.
• Designed for periodic intensive use: The 25000 version is positioned as a stronger, once-weekly treatment rather than a conventional everyday hydrating serum.

Skin Types: Combination • Oily • Normal • Dry skin with adequate barrier support • Experienced active-skincare users
Skin Concerns: Enlarged-looking pores • Blackheads • Whiteheads • Congested-looking skin • Excess sebum • Rough texture • Uneven texture • Dullness • Post-blemish discoloration

Clinical Results:

• 21.1% improvement in pore density according to the supplied test report.
• 21.1% improvement in visible pore appearance according to the supplied test report.
• 15.3% improvement in pore area.
• 16.7% improvement in pore volume.
• 88.7% improvement in dead-skin-cell appearance.
• 51.7% improvement in skin radiance.
• 8.9% improvement in sebum.
• 7.6% improvement in surface hydration.
• 4.1% improvement in skin texture.
• 54.2% improvement in measured skin-barrier parameters.
• 10.4% improvement in line-volume appearance.
• 7.4% improvement in measured melanin pigmentation.
• 4.8% improvement in visible freckles and blemish-related discoloration.
• The supplied test report also states that absorption of applied cosmetic ingredients increased by 242% compared with standalone cosmetic use under the study conditions.
• In a separate 20-person consumer survey, 100% of respondents gave positive feedback regarding the professional-care sensation and overall product satisfaction.
• The consumer survey was conducted by the Global Institute of Dermatological Science between August 24, 2022 and September 21, 2022.
• Individual results may vary, and these cosmetic test results should not be interpreted as permanent changes to pore structure or medical skin treatment.

How to Use:

1. Use preferably in the evening and approximately once per week, according to the supplied directions.
2. After cleansing, apply the ampoule as the first treatment step to clean, dry skin.
3. Apply a small amount over areas with visible pores or uneven texture, or over the face if your skin already tolerates spicule-based products.
4. Avoid the immediate eye area, lips, nostril folds and any broken or significantly irritated skin.
5. Gently press and lightly rub the product into the skin. Do not aggressively massage or scrub.
6. A prickling or tingling sensation can occur because the formula contains Hydrolyzed Sponge micro-spicules.
7. Follow with simple hydrating and barrier-supporting skincare such as a soothing serum and moisturizer.
8. For sensitive skin or first-time spicule users, patch test first and begin with a small amount on a limited area.
9. Avoid strong exfoliating acids, scrubs, Retinol, Retinal or other potentially irritating treatments in the same routine if your skin is sensitive.
10. Do not use immediately after shaving, waxing, professional peeling, microneedling or other procedures that have compromised the skin barrier.
11. If you are new to spicule skincare, avoid combining the product with skincare devices that increase penetration unless specifically advised for your routine.
12. Use broad-spectrum sunscreen every morning, particularly while using exfoliating ingredients.

Key Ingredients:

• Hydrolyzed Sponge: Naturally derived microscopic spicules responsible for the product’s characteristic prickling sensation and micro-needling-inspired skincare concept.
• Lactobacillus Extracellular Vesicles: Listed at 154 ppm and used as part of the formula’s exosome-focused skin-conditioning technology.
• Milk Exosomes: Listed at 10 ppm and included as an additional exosome-derived cosmetic ingredient.
• Niacinamide: Helps improve dullness, uneven-looking tone and the appearance of enlarged pores while supporting the skin barrier.
• Panthenol: Helps soothe, moisturize and maintain barrier comfort.
• Gluconolactone: A PHA that provides gentle surface exfoliation while also supporting hydration.
• Betaine Salicylate: A salicylate-based exfoliating ingredient that helps reduce excess sebum and accumulated surface cells around congested-looking pores.
• Citric Acid: An AHA that can contribute to surface refinement, although it may also function partly as a pH-adjusting ingredient in the formula.
• Ceramide NP: Helps support the skin’s moisture barrier.
• Acetyl Tetrapeptide-5: A cosmetic peptide that provides conditioning and smoothing-focused care.
• Palmitoyl Pentapeptide-4: A peptide commonly used in formulas focused on smoother and firmer-looking skin.
• Palmitoyl Tripeptide-5: Supports elasticity-focused cosmetic care and a more resilient-looking complexion.
• Adenosine: Helps improve the appearance of fine lines and smoother-looking skin.

Ingredients:

Water, Glycereth-26, Dipropylene Glycol, Butylene Glycol, Caprylic/Capric Triglyceride, Niacinamide, Calcium aluminum borosilicate, Hydrolyzed Sponge, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, 1,2-Hexanediol, Caprylyl Glycol, Isohexadecane, Glycerin, Polysorbate 80, Carbomer, Tromethamine, Panthenol, Ethylhexylglycerin, Adenosine, Sorbitan Oleate, Sorbitan Isostearate, Polysorbate 60, Disodium EDTA, Lactobacillus Extracellular Vesicles(154 ppm), Kummerowia Striata Extract, Oenothera Biennis (Evening Primrose) Flower Extract, Ulmus Davidiana Root Extract, Pinus Palustris Leaf Extract, Pueraria Lobata Root Extract, Cinchona Pubescens Bark Extract, Gluconolactone, Betaine Salicylate, Citric Acid, Milk Exosomes(10 ppm), Leptospermum Scoparium Leaf Extract, Hydrogenated Lecithin, Polyglyceryl-10 Laurate, Ceramide NP, Acetyl Tetrapeptide-5, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-5

FAQ:

Q: What does medicube One Day Exosome Shot Pore Ampoule 25000 do?
A: It is an intensive spicule-based treatment designed to improve the appearance of enlarged pores, congestion, excess sebum, rough texture, dullness and uneven-looking skin.

Q: What makes the 25000 version different from a regular serum?
A: It is positioned as a stronger, periodic pore treatment using Hydrolyzed Sponge micro-spicules together with exosome-derived ingredients and exfoliating actives rather than as a simple everyday moisturizing serum.

Q: Should I use it every day?
A: No. The supplied directions for the 25000 version recommend approximately once-weekly use.

Q: Why does the serum tingle?
A: Hydrolyzed Sponge contains microscopic spicule structures that create the characteristic prickling or tingling sensation when they contact the skin.

Q: Does tingling mean the product is working better?
A: Not necessarily. Tingling is primarily a physical sensation associated with the spicules. More tingling does not mean better results and excessive discomfort should not be deliberately encouraged.

Q: How long can the tingling last?
A: Sensation varies by individual and may continue for some time after application. Reduce the amount or frequency if the sensation becomes uncomfortable.

Q: What is the difference between normal tingling and irritation?
A: Mild prickling is expected with spicules. Intense burning, pronounced swelling, persistent itching, worsening redness or significant pain should be treated as irritation rather than something to push through.

Q: Does this product contain real needles?
A: No medical needles are used. The formula contains Hydrolyzed Sponge, which consists of microscopic naturally derived spicule structures and creates a microneedling-inspired surface sensation.

Q: Is this the same as professional microneedling?
A: No. A cosmetic spicule ampoule is not equivalent to professional microneedling performed with medical or cosmetic needle devices.

Q: Do the spicules remain permanently in the skin?
A: No. According to the supplied product information, residual spicules naturally disappear as the skin’s surface cells shed over the following days.

Q: Should I wash the serum off?
A: No. It is a leave-on treatment. Follow it with hydrating and moisturizing skincare.

Q: Should I apply it before or after toner?
A: The supplied instructions vary slightly, but for intensive use the brand recommends applying the Exosome Shot as the first treatment step after cleansing. Beginners may use a simple hydrating toner first if needed for comfort.

Q: Does it contain exosomes?
A: The supplied INCI clearly lists Lactobacillus Extracellular Vesicles and Milk Exosomes.

Q: What are Lactobacillus Extracellular Vesicles?
A: They are microscopic vesicle structures derived from Lactobacillus and are used in this cosmetic formula as skin-conditioning ingredients associated with its exosome technology.

Q: How much Lactobacillus Extracellular Vesicles does it contain?
A: The supplied INCI lists Lactobacillus Extracellular Vesicles at 154 ppm, equivalent to 0.0154%.

Q: Does it contain Milk Exosomes?
A: Yes. Milk Exosomes are listed at 10 ppm, equivalent to 0.001%.

Q: Does the ingredient list show 25,000 ppm of exosomes?
A: The product is marketed as the 25000 version, but the standardized INCI directly specifies 154 ppm Lactobacillus Extracellular Vesicles and 10 ppm Milk Exosomes. The supplied ingredient list does not identify 25,000 ppm as the concentration of these two individually named exosome ingredients.

Q: Is the product vegan?
A: No. Milk Exosomes are clearly listed in the supplied INCI, so the formula should not be described as vegan.

Q: Does it contain Niacinamide?
A: Yes. Niacinamide is clearly listed and supports brighter, more even-looking skin and refined-looking pores.

Q: Does it contain peptides?
A: Yes. The supplied INCI contains three clearly named peptides: Acetyl Tetrapeptide-5, Palmitoyl Pentapeptide-4 and Palmitoyl Tripeptide-5.

Q: Does it contain Ceramides?
A: Yes. Ceramide NP is included to support the moisture barrier.

Q: Does it contain Panthenol?
A: Yes. Panthenol provides soothing and moisturizing barrier support.

Q: Does it contain AHA, BHA or PHA?
A: The formula contains Gluconolactone as a PHA, Betaine Salicylate as a salicylate-based exfoliating ingredient, and Citric Acid, which is chemically an AHA although it can also serve as a pH adjuster.

Q: Does it contain Salicylic Acid?
A: Salicylic Acid itself is not listed. The formula contains Betaine Salicylate.

Q: Can it help blackheads and whiteheads?
A: The exfoliating ingredients and pore-focused formula can help reduce accumulated surface cells and excess sebum that contribute to clogged-looking pores, blackheads and whiteheads.

Q: Can it permanently remove blackheads?
A: No. Blackheads and congestion can recur as sebum and dead surface cells accumulate again.

Q: Can it shrink pores permanently?
A: No. Skincare cannot permanently change the anatomical size or number of pores, although the product can make them appear less visible by improving texture, sebum, hydration and surrounding skin condition.

Q: What pore results were measured?
A: The supplied report states improvements of 21.1% in pore density and visible pore appearance, 15.3% in pore area and 16.7% in pore volume.

Q: Did it improve skin texture?
A: Yes. The supplied testing reported a 4.1% improvement in texture and an 88.7% improvement in dead-skin-cell appearance.

Q: Did it improve radiance?
A: The supplied test report states a 51.7% improvement in skin radiance.

Q: Did it improve the skin barrier?
A: According to the supplied report, measured skin-barrier parameters improved by 54.2% under the study conditions.

Q: Does it really increase skincare absorption?
A: The supplied Medicube report states a 242% increase in absorption of applied cosmetic ingredients compared with standalone cosmetic use under its test conditions. This does not mean every ingredient or every skincare product will absorb 242% more in normal use.

Q: Should I use strong active serums immediately after it to maximize absorption?
A: Not necessarily. Because the spicule treatment may temporarily make skin more reactive, simple hydrating and barrier-supporting products are the safer choice immediately afterward, particularly for beginners.

Q: Can I use Retinol or Retinal with it?
A: It is preferable not to layer a strong retinoid in the same routine when first using this product. Alternate nights if combining the two causes dryness, burning or irritation.

Q: Can I use AHA or BHA with it?
A: The product already contains exfoliating ingredients. Adding another strong acid treatment in the same routine can unnecessarily increase irritation, especially when combined with spicules.

Q: Can I use Vitamin C with it?
A: A gentle Vitamin C derivative may be tolerated by experienced users, but sensitive skin may prefer Vitamin C at another time and simple hydration immediately after the Exosome Shot.

Q: Can I use Niacinamide after it?
A: Yes, although the ampoule already contains Niacinamide. A simple hydrating Niacinamide product may be compatible if your skin tolerates it.

Q: Can I use Medicube AGE-R devices with it?
A: The supplied instructions advise users who are not accustomed to spicule skincare not to combine it with AGE-R devices. Experienced users should follow Medicube’s device-specific instructions carefully.

Q: Can I use the AGE-R Booster Pro Air Shot Mode before it?
A: Medicube’s supplied directions suggest this combination for experienced users, but it may intensify the skincare experience. Beginners and sensitive skin should avoid combining penetration-enhancing methods initially.

Q: Can I use it after microneedling?
A: No. Do not apply it to freshly microneedled, peeled, lasered or otherwise compromised skin unless a qualified professional specifically advises you to do so.

Q: Can I use it after shaving or waxing?
A: Avoid immediate use after shaving or waxing because the skin may be more sensitive and the spicules can cause substantially more discomfort.

Q: Is it suitable for oily skin?
A: Yes. Its pore, sebum and texture-focused benefits make it particularly relevant for oily and combination skin.

Q: Is it suitable for dry skin?
A: It can be used on dry skin, but maintaining a strong moisture barrier is important. Follow with a hydrating, barrier-supporting moisturizer.

Q: Is it suitable for sensitive skin?
A: Sensitive skin should approach the 25000 version cautiously. Patch testing, limited-area application and low frequency are recommended because the spicules and exfoliating ingredients may cause significant sensation.

Q: Is it suitable for acne-prone skin?
A: The supplied product information states that it has undergone non-comedogenic testing. It may suit acne-prone skin concerned with congestion and pores, but do not apply aggressively over broken or inflamed blemishes.

Q: Is it non-comedogenic?
A: According to the supplied product information, the product has undergone non-comedogenic testing.

Q: Is it fragrance-free?
A: No Fragrance or Parfum is listed in the supplied INCI.

Q: Does it contain essential oils?
A: No clearly identified aromatic essential oils are listed in the supplied INCI.

Q: Does it contain drying alcohol?
A: Ethanol and Alcohol Denat. are not listed.

Q: Does it contain artificial colour?
A: The supplied product information states that it contains no artificial colour.

Q: Can I apply it around the eyes?
A: No. Avoid the immediate eye area because the spicules can cause significant discomfort on delicate skin.

Q: What should I apply after it?
A: Follow with simple hydrating and soothing products and finish with a moisturizer that supports the skin barrier.

Q: Do I need sunscreen while using it?
A: Yes. Daily broad-spectrum sunscreen is recommended, particularly because the routine includes exfoliating ingredients and intensive texture care.

Q: Where can I buy medicube skincare in Cyprus?
A: You can find medicube One Day Exosome Shot Pore Ampoule 25000 at Just Cosmetics, together with a curated selection of Korean Cosmetics in Cyprus.